Article

Functional properties and pharmacology of extrasynaptic GABA-A receptors

2012-01-01

Abstract excerpt

The “ambient” GABA that is present in the extracellular space surrounding all neurons of the brain is believed to be capable of persistently activating high‐affinity extrasynaptic GABA-A receptors to generate a tonic membrane conductance. This generates a form of shunting inhibition that is capable of influencing cellular and network excitability. Extrasynaptic δ subunit-containing GABA-A receptors are known to ge...

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Identifiers and source

Literature Corpus work: 79aa3405-962f-5e26-9eb8-23f73a53f691
DOI: 10.25560/9560

Open publication

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