The role of GABAA receptor biogenesis, structure and function in epilepsy.

Abstract excerpt

Maintaining the correct balance in neuronal activation is of paramount importance to normal brain function. Imbalances due to changes in excitation or inhibition can lead to a variety of disorders ranging from the clinically extreme (e.g. epilepsy) to the more subtle (e.g. anxiety). In the brain, the most common inhibitory synapses are regulated by GABAA (gamma-aminobutyric acid type A) receptors, a role...

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