Article

The Role of 1- <i>O</i> -Acylceramide NP in Structural Organization and Permeability of the Stratum Corneum Lipid Matrix

2022-12-10

Abstract excerpt

<h4>ABSTRACT</h4> The extracellular lipid matrix in the stratum corneum (SC) is crucial for generating a skin barrier (permeability) function. The lipid matrix contains three major components; ceramides, cholesterol, and free fatty acids. The broad diversity of ceramides depends on their molecular structures ( e.g ., hydroxylations and chain lengths) and plays a critical role in maintaining the structural integr...

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Literature Corpus work: 79975e76-3567-5d3e-a928-2f93b4f5f2a0
DOI: 10.1101/2022.12.06.519381

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