Towards understanding of NK cell antigenic specificity

Abstract excerpt

NK cells can form clonal populations demonstrating features of adaptive immunity, including long-term memory and at least partial antigenic specificity. Given the limited individual diversity of activating receptors, the nature of NK cell antigenic specificity remains elusive. To explore this riddle, we combined scRNA-Seq of ex vivo FACS-sorted NK cell subsets expressing specific KIR receptors, single-cell clonin...

Topics

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• Cluster Analysis
• Environment
• Gene Expression Regulation
• Histocompatibility Antigens Class I
• Immunologic Memory
• Killer Cells, Natural
• Mass Spectrometry
• Receptors, Natural Killer Cell

Identifiers and source

Literature Corpus work

79699d19-a6cc-596d-9ff9-182c76d93d0d

DOI

10.64898/2026.05.29.728791