Homing and Engraftment of Hematopoietic Stem Cells Following Transplantation: A Pre-clinical Perspective

Abstract excerpt

Hematopoietic stem cell (HSC) transplantation (HSCT) is used to treat various hematologic disorders. Use of genetically modified mouse models of hematopoietic cell transplantation have been critical in our fundamental understanding of HSC biology and developing approaches for human patients. Pre-clinical studies in animal models provide insight into the journey of transplanted HSCs from infusion to engraftment in...

Topics

Open a Topic to create a Post that cites this publication.

• CAR-T cell therapy research
• Chemokine receptors and signaling
• Hematopoietic Stem Cell Transplantation
• Mesenchymal stem cell research
• Pluripotent Stem Cells Research
• T-cell and B-cell Immunology
• Virus-based gene therapy research
• Zebrafish Biomedical Research Applications

Identifiers and source

Literature Corpus work

7961c9d2-339c-5c1d-865e-ee9ef5f2ec75

DOI

10.20944/preprints202312.2125.v1