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Article

The Niche as a Target for Hematopoietic Manipulation and Regeneration

9 Sept 2011

Abstract excerpt

Hematopoietic stem cells (HSCs), rare primitive cells capable of reconstituting all blood cell lineages, are the only stem cells currently routinely used for therapeutic purposes. Clinical experience has shown that HSC number is an important limiting factor in treatment success. Strategies to expand HSCs are of great clinical appeal, as they would improve therapeutic use of these cells in stem cell...

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PMID: 21902610
DOI: 10.1089/ten.teb.2011.0197

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