Article

Cross-phenotype relationship between opioid use disorder and suicide attempts: new evidence from polygenic association and Mendelian randomization analyses

2022-11-07

Abstract excerpt

<h4>IMPORTANCE</h4> Clinical epidemiological studies have found high rates of comorbidity between suicide attempts (SA) and opioid use disorder (OUD). However, the patterns of correlation and causation between them are still not clear due to psychiatric confounding. <h4>OBJECTIVE</h4> To investigate the pairwise associations and interrogate the potential bidirectional relationship between OUD and SA using genetica...

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Literature Corpus work: 794d3b34-9742-5f48-90d2-14e4f282cc60
DOI: 10.1101/2022.11.03.22281876

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