In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders.

Abstract excerpt

Suicide is a significant public health problem that usually co-occurs with major psychiatric disorders. Suicidal behaviors have heritability of 30-50%, and the largest genome-wide association studies identified 12 loci linked to suicide attempts (SA). These findings indicate shared genetic architecture among SA and psychiatric disorders. We analyzed public GWAS summary statistics of SA, major depressive disorder...

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• Attention Deficit Disorder with Hyperactivity
• Bipolar Disorder
• Genetic Risk Score
• Major Depressive Disorder
• Mental Disorders