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Cell-free DNA (cfDNA) and exosome profiling from a year-long human spaceflight reveals circulating biomarkers

2020-11-08

Abstract excerpt

The health impact of prolonged space flight on the human body is not well understood. Liquid biopsies based on cell-free DNA (cfDNA) or exosome analysis provide a noninvasive approach to monitor the dynamics of genomic, epigenomic and proteomic biomarkers, and the occurrence of DNA damage, physiological stress, and immune responses. To study the molecular consequences of spaceflight we profiled cfDNA isolated from...

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Literature Corpus work
7945ac8d-c867-5409-94b3-266961710108
DOI
10.1101/2020.11.08.373530
Open publication

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Cell-free DNA (cfDNA) and exosome profiling from a year-long human spaceflight reveals circulating biomarkersDOI 10.1101/2020.11.08.373530
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