Article

Impact of low-frequency coding variants on human facial shape

2020-07-30

Abstract excerpt

The contribution of low-frequency variants to the genetic architecture of normal-range facial traits is unknown. We studied the influence of low-frequency coding variants (MAF < 1%) on multi-dimensional facial shape phenotypes in 2329 healthy Europeans. We used MultiSKAT o scan the exome for face-associated low-frequency variants in a gene-based manner. Seven genes ( AR, CARS2, FTSJ1, HFE, LTB4R, TELO2, NECTIN1 )...

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Literature Corpus work: 78d9488c-2b5d-5ace-8033-d2afa329e052
DOI: 10.1101/2020.07.30.227769

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