Article
Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology.
PLoS genetics - 1 Aug 2016
Shaffer John R, Orlova Ekaterina, Lee Myoung Keun, Leslie Elizabeth J, Raffensperger Zachary D, Heike Carrie L, Cunningham Michael L, Hecht Jacqueline T, Kau Chung How, Nidey Nichole L, Moreno Lina M, Wehby George L, Murray Jeffrey C, Laurie Cecelia A, Laurie Cathy C, Cole Joanne, Ferrara Tracey, Santorico Stephanie, Klein Ophir, Mio Washington, Feingold Eleanor, Hallgrimsson Benedikt, Spritz Richard A, Marazita Mary L, Weinberg Seth M
Abstract excerpt
Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet little is known about how specific genetic variants relate to the phenotypic expression of many common facial features. We conducted genome-wide association meta-analyses of 20 quantitative facial measurements derived from the 3D surface images of 3118 healthy individuals of European ancestry belonging to two US cohorts....
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