Article
A multi-ancestry GWAS meta-analysis of facial features and its application in predicting archaic human features.
Journal of genetics and genomics = Yi chuan xue bao - 1 Apr 2025
Du Siyuan, Chen Jieyi, Li Jiarui, Qian Wei, Wu Sijie, Peng Qianqian, Liu Yu, Pan Ting, Li Yi, Hadi Sibte Syed, Tan Jingze, Yuan Ziyu, Wang Jiucun, Tang Kun, Wang Zhuo, Wen Yanqin, Dong Xinran, Zhou Wenhao, Ruiz-Linares Andrés, Shi Yongyong, Jin Li, Liu Fan, Zhang Manfei, Wang Sijia
Abstract excerpt
Facial morphology, a complex trait influenced by genetics, holds great significance in evolutionary research. However, due to limited fossil evidence, the facial characteristics of Neanderthals and Denisovans have remained largely unknown. In this study, we conduct a large-scale multi-ethnic meta-analysis of the genome-wide association study (GWAS), including 9674 East Asians and 10,115 Europeans, quantitatively...
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