Article
A genome-wide association study identifies five loci influencing facial morphology in Europeans.
PLoS genetics - 1 Sept 2012
Liu Fan, van der Lijn Fedde, Schurmann Claudia, Zhu Gu, Chakravarty M Mallar, Hysi Pirro G, Wollstein Andreas, Lao Oscar, de Bruijne Marleen, Ikram M Arfan, van der Lugt Aad, Rivadeneira Fernando, Uitterlinden André G, Hofman Albert, Niessen Wiro J, Homuth Georg, de Zubicaray Greig, McMahon Katie L, Thompson Paul M, Daboul Amro, Puls Ralf, Hegenscheid Katrin, Bevan Liisa, Pausova Zdenka, Medland Sarah E, Montgomery Grant W, Wright Margaret J, Wicking Carol, Boehringer Stefan, Spector Timothy D, Paus Tomáš, Martin Nicholas G, Biffar Reiner, Kayser Manfred
Abstract excerpt
Inter-individual variation in facial shape is one of the most noticeable phenotypes in humans, and it is clearly under genetic regulation; however, almost nothing is known about the genetic basis of normal human facial morphology. We therefore conducted a genome-wide association study for facial shape phenotypes in multiple discovery and replication cohorts, considering almost ten thousand individuals of European...
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