Article

Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis

2024-08-09

Abstract excerpt

Many inflammatory genes in the immune system are clustered in the genome. The 3D genome architecture of these clustered genes likely plays a critical role in their regulation and alterations to this structure may contribute to diseases where inflammation is poorly controlled. Alcohol-associated hepatitis (AH) is a severe inflammatory disease that contributes significantly to morbidity in alcohol associated liver d...

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Literature Corpus work: 78c9ab41-0ecd-5886-bb26-5818584d3790
DOI: 10.1101/2024.08.07.607014

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