Article

Assessing In House Comprehensive Genomic Profiling by Liquid Biopsy for NSCLC Patients

2025-05-06

Abstract excerpt

<title>Abstract</title> <p>Liquid biopsy has emerged as a valuable tool for detecting therapeutic targets and resistance mechanisms. In this study, we aimed at evaluating the analytical performance of the TruSight Oncology 500 ctDNA (TSO500) compared to the FDA-approved Guardant360 CDx (G360) in detecting actionable alterations in NSCLC patients progressing on targeted therapies. We analysed 44 plasma samples fro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 78a00c2c-69b3-5d49-a9c7-5a6ea6cff0f3
DOI: 10.21203/rs.3.rs-6264683/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Assessing In House Comprehensive Genomic Profiling by Liquid Biopsy for NSCLC PatientsDOI 10.21203/rs.3.rs-6264683/v1Read

The significance of using liquid biopsy to improve treatment outcomes for metastatic patientsSemantic proximity Read

Liquid biopsy comprehensive genomic profiling of lung cancer in the Italian population: A real-world experience.Semantic proximity Read

An update on liquid biopsy analysis for diagnostic and monitoring applications in non-small cell lung cancer.Semantic proximity Read

Circulating tumor DNA to monitor treatment response in solid tumors and advance precision oncologySemantic proximity Read

Implementation of a 1021-gene liquid biopsy assay for real-world tumor genomic profiling in oncology practice.Semantic proximity Read

Outcomes in oncogenic-addicted advanced NSCLC patients with actionable mutations identified by liquid biopsy genomic profiling using a tagged amplicon-based NGS assay.Semantic proximity Read

Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer.Semantic proximity Read

Combining tumor genomic and transcriptomic analysis with liquid biopsy ctDNA monitoring: analytical validation and clinical insightsSemantic proximity Read

Monitoring Somatic Genetic Alterations in Circulating Cell-Free DNA/RNA of Patients with "Oncogene-Addicted" Advanced Lung Adenocarcinoma: A Real-World Clinical Study.Semantic proximity Read

Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment.Semantic proximity Read

Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNASemantic proximity Read

Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types.Semantic proximity Read