Article

Combining tumor genomic and transcriptomic analysis with liquid biopsy ctDNA monitoring: analytical validation and clinical insights

2025-07-14

Abstract excerpt

<h4>Background</h4> Comprehensive genomic profiling (CGP) is a time– and tissue-efficient method to help guide precision oncology. To enhance clinical utility of CGP, we investigated performance of a novel strategy integrating tumor DNA and mRNA profiling, together with liquid biopsy ctDNA monitoring. <h4>Methods</h4> Genomic DNA and mRNA simultaneously extracted from 604 archived tissue samples of 12 cancer typ...

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Literature Corpus work: 53a7b0dc-bbd5-5bcc-ab68-89b559dc4fc7
DOI: 10.1101/2025.07.12.25331415

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