Article
Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment.
Molecular oncology - 1 Jun 2021
Filipska Martyna, Rosell Rafael
Abstract excerpt
Over the past decade, substantial developments have been made in the detection of circulating tumor DNA (ctDNA)-cell-free DNA (cfDNA) fragments released into the circulation from tumor cells and displaying the genetic alterations of those cells. As such, ctDNA detected in liquid biopsies serves as a powerful tool for cancer patient stratification, therapy guidance, detection of resistance, and relapse monitoring....
Topics
- Cell-Free Nucleic Acids
- Circulating Tumor DNA
- Early Detection of Cancer
- Humans
- Liquid Biopsy
- Lung Neoplasms
- Mutation
- Precision Medicine