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Outcomes in oncogenic-addicted advanced NSCLC patients with actionable mutations identified by liquid biopsy genomic profiling using a tagged amplicon-based NGS assay.

PloS one - 1 Jan 2020

Remon Jordi, Swalduz Aurelie, Planchard David, Ortiz-Cuaran Sandra, Mezquita Laura, Lacroix Ludovic, Jovelet Cecile, Rouleau Etienne, Leonce Camille, De Kievit Frank, Morris Clive, Jones Greg, Mercier Kelly, Howarth Karen, Green Emma, Pérol Maurice, Saintigny Pierre, Besse Benjamin

Abstract excerpt

Circulating tumor DNA (ctDNA)-based molecular profiling is rapidly gaining traction in clinical practice of advanced cancer patients with multi-gene next-generation sequencing (NGS) panels. However, clinical outcomes remain poorly described and deserve further validation with personalized treatment of patients with genomic alterations detected in plasma ctDNA. Here, we describe the outcomes, disease control rate...

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Identifiers

PMID: 32525942
DOI: 10.1371/journal.pone.0234302
PMCID: PMC7289417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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