Article

Romidepsin exhibits anti-esophageal squamous cell carcinoma activity through the DDIT4-mTORC1 pathway

2023-12-19

Abstract excerpt

<title>Abstract</title> <p>Esophageal squamous cell carcinoma (ESCC) is one of the most common human malignancies worldwide and is associated with high morbidity and mortality. Current treatment options are limited, highlighting the need for development of novel effective agents. Here, a high-throughput drug screening (HTS) was performed using ESCC cell lines in both two- and three-dimensional culture systems to...

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Literature Corpus work: 7861eeb6-5789-5c94-8127-b4b31f198431
DOI: 10.21203/rs.3.rs-3719026/v1

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