Article

Identification of Key Genes and Pathways Governing T-DM1 Resistance in OE-19 Esophageal Cancer Cells through Bioinformatics Analysis

2023-10-17

Abstract excerpt

<h4>Introduction: </h4> Esophageal Cancer (EC) ranks among the most common malignancies worldwide. Most EC patients acquire drug resistance to chemotherapy either intrinsically or acquired after T-DM1 treatment, which shows that increasing or decreasing the expression of particular genes might influence chemotherapeutic sensitivity or resistance. Therefore, gaining a deeper understanding of the altered expression...

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Literature Corpus work: e630c36c-cb26-5292-8865-076a814f28f4
DOI: 10.21203/rs.3.rs-3423572/v1

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