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Article

Manipulating Histone Acetylation Leads to Adverse Effects in Hemangiosarcoma Cells

2021-12-11

Abstract excerpt

Canine hemangiosarcoma (HSA) is a malignant tumour derived from endothelial cells. No effective treatment has yet been developed because of the lack of understanding of its pathogenesis. Histone acetylation, an epigenetic modification, is highly associated with cancer pathogenesis. Manipulating histone acetylation by histone deacetylase inhibitors (HDACi) or bromodomain and extraterminal domain inhibitors (BETi) i...

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Literature Corpus work
785ec1d8-ca48-5675-845f-f0947454b26c
DOI
10.1101/2021.12.10.472173
Open publication

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