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Histone Deacetylases: Anti-Angiogenic Targets in Cancer Therapy

16 Nov 2010

Abstract excerpt

Judah Folkman was the first in 1971 to observe and report that cancer growth and dissemination were dependent on angiogenesis - the formation of new blood vessels from pre-existing vasculature. For almost 40 years, this concept has inspired generations of researchers to identify anti-angiogenic molecules that could be used therapeutically to stop blood vessels formation and starve tumors of nutrients and oxygen....

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PMID: 20718701
DOI: 10.2174/156800910793358014

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