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Histone deacetylase inhibitors as a novel therapeutic approach for pheochromocytomas and paragangliomas

1 Jan 2022

Abstract excerpt

Epigenetic mechanisms, such as DNA methylation and histone modifications (e.g., acetylation and deacetylation), are strongly implicated in the carcinogenesis of various malignancies. During transcription, the expression and functionality of coding gene products are altered following the histone acetylation and deacetylation. These processes are regulated by histone acetyltransferases (HATs) and histone...

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PMID: 37305348
DOI: 10.32604/or.2022.026913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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