Article

Protosequences in brain organoids model intrinsic brain states

2023-12-30

Abstract excerpt

Neuronal firing sequences are thought to be the basic building blocks of neural coding and information broadcasting within the brain. However, when sequences emerge during neurodevelopment remains unknown. We demonstrate that structured firing sequences are present in spontaneous activity of human and murine brain organoids and ex vivo neonatal brain slices from the murine somatosensory cortex. We observed a bala...

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Literature Corpus work: af07ec1f-11c1-5014-b769-3e84e3aa0acb
DOI: 10.1101/2023.12.29.573646

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