Article
Spontaneous Neuronal Network Persistent Activity in the Neocortex: A(n) (Endo)phenotype of Brain (Patho)physiology.
Advances in experimental medicine and biology - 1 Jan 2000
Rigas Pavlos, Leontiadis Leonidas J, Tsakanikas Panagiotis, Skaliora Irini
Abstract excerpt
Abnormal synaptic homeostasis in the cerebral cortex represents a risk factor for both psychiatric and neurodegenerative disorders, from autism and schizophrenia to Alzheimer's disease. Neurons via synapses form recurrent networks that are intrinsically active in the form of oscillating activity, visible at increasingly macroscopic neurophysiological levels: from single cell recordings to the local field...
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