Article

Ablation of the choroid plexus attenuates hydrocephalus induced parenchymal edema but moderately reduces postnatal hippocampal neurogenesis

2026-04-01

Abstract excerpt

<h4>Background</h4> Choroid plexus (ChP) produces cerebrospinal fluid (CSF) and regulates brain development and adult subventricular zone (SVZ) neurogenesis, but its role in postnatal hippocampal subgranular zone (SGZ) neurogenesis is not well understood. Neonatal hydrocephalus, a devastating neurological condition characterized by excessive accumulation of CSF in the brain, is sometimes treated in conjunction wi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 77f817de-68a2-57d4-a5d8-d10d02ecedb3
DOI: 10.64898/2026.03.30.714236

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ablation of the choroid plexus attenuates hydrocephalus induced parenchymal edema but moderately reduces postnatal hippocampal neurogenesisDOI 10.64898/2026.03.30.714236Read

Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam.Semantic proximity Read

Fetal Brain-directed AAV Gene Therapy Results in Rapid, Robust, and Persistent Transduction of Mouse Choroid Plexus EpitheliaSemantic proximity Read

Adeno-associated viruses (AAVs) induce dose-dependent neonatal ventriculomegaly following intracerebroventricular administrationSemantic proximity Read

Hydrocephalus in Connection to Genetic Mutation in Cranial Neural Crest Cells.Semantic proximity Read

Understanding and Modeling the Pathophysiology of Hydrocephalus: In Search of Better Treatment OptionsSemantic proximity Read

In vivo analysis of choroid plexus morphogenesis in zebrafish.Semantic proximity Read

Choroid plexus APP regulates adult brain proliferation and animal behaviorSemantic proximity Read

Characterization of a model of hydrocephalus in transgenic mice.Semantic proximity Read

Murine <i>MPDZ</i> -Linked Hydrocephalus is Caused by Hyperpermeability of the Choroid PlexusSemantic proximity Read

Neonatal but not juvenile gene therapy reduces seizures and prolongs lifespan in SCN1B–Dravet syndrome miceSemantic proximity Read

Crb2-dependent progenitor adhesion safeguards ventricular lining integrity and prevents hydrocephalusSemantic proximity Read

Genetic and molecular mechanisms of hydrocephalusSemantic proximity Read