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Article

Characterization of a model of hydrocephalus in transgenic mice.

Journal of neurosurgery - 1 Dec 1999

Cohen A R, Leifer D W, Zechel M, Flaningan D P, Lewin J S, Lust W D

Abstract excerpt

OBJECT: The purpose of this study was to elucidate the pathophysiological characteristics of hydrocephalus in a new transgenic model of mice created to overproduce the cytokine transforming growth factor-beta1 (TGFbeta1) in the central nervous system (CNS). METHODS: Galbreath and colleagues generated transgenic mice that overexpressed TGFbeta1 in the CNS in an effort to examine the role of this cytokine in the...

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Source

Identifiers

PMID: 10584844
DOI: 10.3171/jns.1999.91.6.0978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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