Article

Computationally defined and <i>in vitro</i> validated putative genomic safe harbour loci for transgene expression in human cells

2021-12-09

Abstract excerpt

<h4>Summary</h4> Selection of the target site is an inherent question for any project aiming for directed transgene integration. Genomic safe harbour (GSH) loci have been proposed as safe sites in the human genome for transgene integration. Although several sites have been characterised for transgene integration in the literature, most of these do not meet criteria set out for a GSH and the limited set that do ha...

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Literature Corpus work: 77eb9c83-b8c7-53f5-b148-72d756dbe953
DOI: 10.1101/2021.12.07.471422

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