Article

Validation of caprine H11 and Rosa26 safe harbor loci via CRISPR- based system: Investigations on stable transgene expression and genetic biosafety

2025-05-28

Abstract excerpt

<title>Abstract</title> <p>CRISPR/Cas9 technology is an efficient tool for livestock gene editing. However, host genome function can be disrupted by the random integration of exogenous genes. To circumvent this issue, site-specific integration is required. This study established a multi-dimensional assessment system to evaluate the biological applicability of H11/Rosa26 safe harbor loci as targeted integration pl...

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Literature Corpus work: 0ecf1000-9081-584a-94aa-49ffd29237df
DOI: 10.21203/rs.3.rs-6618888/v1

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Validation of caprine H11 and Rosa26 safe harbor loci via CRISPR- based system: Investigations on stable transgene expression and genetic biosafetyDOI 10.21203/rs.3.rs-6618888/v1Read

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