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Single-cell dissection of cellular and molecular features underlying human cervical squamous cell carcinoma initiation and progression

27 Jan 2023

Abstract excerpt

Cervical squamous cell carcinoma (CESC) is a prototypical human cancer with well-characterized pathological stages of initiation and progression. However, high-resolution knowledge of the transcriptional programs underlying each stage of CESC is lacking, and important questions remain. We performed single-cell RNA sequencing of 76,911 individual cells from 13 samples of human cervical tissues at various stages of...

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PMID: 36706185
DOI: 10.1126/sciadv.add8977

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