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Single‐cell dissection of cervical cancer reveals key subsets of the tumor immune microenvironment

10 Jul 2023

Abstract excerpt

The tumor microenvironment (TME) directly determines patients' outcomes and therapeutic efficiencies. An in-depth understanding of the TME is required to improve the prognosis of patients with cervical cancer (CC). This study conducted single-cell RNA and TCR sequencing of six-paired tumors and adjacent normal tissues to map the CC immune landscape. T and NK cells were highly enriched in the tumor area and...

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PMID: 37427448
DOI: 10.15252/embj.2022110757

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