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Fetal liver hematopoiesis: from development to delivery

17 Feb 2021

Abstract excerpt

Clinical transplants of hematopoietic stem cells (HSC) can provide a lifesaving therapy for many hematological diseases; however, therapeutic applications are hampered by donor availability. In vivo, HSC exist in a specified microenvironment called the niche. While most studies of the niche focus on those residing in the bone marrow (BM), a better understanding of the fetal liver niche during development is vital...

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PMID: 33597015
DOI: 10.1186/s13287-021-02189-w

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