Article

Striatal (a-)Symmetry Reveals Gender-Specific Autonomic Vulnerabilities in early Parkinson’s Disease

2025-07-14

Abstract excerpt

<title>Abstract</title> <p>Autonomic symptoms are common in Parkinson’s disease and vary according to patterns of dopaminergic neurodegeneration. Based on the alpha-Synuclein Origin site and Connectome model, which distinguishes “brain-first” and “body-first” Parkinson’s disease phenotypes, this study investigates how striatal denervation asymmetry and gender influence autonomic dysfunction profiles in early-stag...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 775e2bf3-8df0-5f17-b978-d73ddb7ba904
DOI: 10.21203/rs.3.rs-6953991/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Striatal (a-)Symmetry Reveals Gender-Specific Autonomic Vulnerabilities in early Parkinson’s DiseaseDOI 10.21203/rs.3.rs-6953991/v1Read

The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort.Semantic proximity Read

The α-Synuclein Origin and Connectome Model (SOC Model) of Parkinson's Disease: Explaining Motor Asymmetry, Non-Motor Phenotypes, and Cognitive Decline.Semantic proximity Read

The noradrenergic subtype of Parkinson disease: from animal models to clinical practice.Semantic proximity Read

Sex differences in Parkinson’s disease: Features on clinical symptoms, treatment outcome, sexual hormones and geneticsSemantic proximity Read

Longitudinal relationships between non-motor symptoms and biomarkers as a function of motor symptom asymmetry in early Parkinson’s diseaseSemantic proximity Read

Body-First Subtype of Parkinson's Disease with Probable REM-Sleep Behavior Disorder Is Associated with Non-Motor Dominant Phenotype.Semantic proximity Read

Laterality In Parkinson’s Disease: A Neuropsychological ReviewSemantic proximity Read

Gender differences in the prevalence of Parkinson’s diseaseSemantic proximity Read

Focal and diffuse clinical subtypes in early-stage Parkinson’s disease: a one-year longitudinal studySemantic proximity Read

Autonomic dysfunction in genetic forms of synucleinopathies.Semantic proximity Read

The challenges with the identification of Parkinson's disease subtypes.Semantic proximity Read

Differences in the presentation and progression of Parkinson’s disease by sexSemantic proximity Read