Article
Autonomic dysfunction in genetic forms of synucleinopathies.
Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2018
Chelban Viorica, Vichayanrat Ekawat, Schottlaende Lucia, Iodice Valeria, Houlden Henry
Abstract excerpt
The discovery of genetic links between alpha-synuclein and PD has opened unprecedented opportunities for research into a new group of diseases, now collectively known as synucleinopathies. Autonomic dysfunction, including cardiac sympathetic denervation, has been reported in familial forms of synucleinopathies that have Lewy bodies at the core of their pathogenesis. SNCA mutations and multiplications, LRRK2...
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