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Mining and manipulation of antibiotic biosynthesis in Streptomyces

2019-01-01

Abstract excerpt

New small-molecule drugs are needed, both to address existing disease and to combat the rise of antibiotic resistance in pathogenic microbes. A major source of antibiotics and other valuable therapeutic agents remains the natural products produced by Streptomyces and allied bacteria. The advent of genome-level sequencing has changed how such bioactive products are identified in two ways: first, by enabling new app...

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Literature Corpus work
774b61c0-0114-5938-b674-317f0a3cda50
DOI
10.17863/cam.39807
Open publication

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Mining and manipulation of antibiotic biosynthesis in StreptomycesDOI 10.17863/cam.39807
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