Article
Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
26 Oct 2024
Abstract excerpt
Fungal infections pose a great threat to public health and there are only four main types of antifungal drugs, which are often limited with toxicity, drug-drug interactions and antibiotic resistance. Streptomyces is an important source of antibiotics, represented by the clinical drug amphotericin B. Here we report the discovery of alligamycin A (1) as an antifungal compound from the rapamycin-producer...
Topics
Join the communities discussing this publication.