Article

A standardised framework to identify optimal animal models for efficacy assessment in drug development

2018-08-01

Abstract excerpt

<h4>Introduction</h4> Poor translation of efficacy data derived from animal models is a potential contributor to costly and unnecessary attrition in clinical trials. <h4>Objectives</h4> To develop a tool to assess, validate and compare the clinical translatability of animal models used for the preliminary assessment of efficacy. <h4>Design and Results</h4> We conducted an exploratory literature search to identi...

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Literature Corpus work: 8d31640e-05b9-56d4-b22e-909d16fb90a1
DOI: 10.1101/382366

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