Article

Scutellarin inhibits ferroptosis by promoting cellular antioxidant capacity through regulating the Nrf2 signaling

2025-06-26

Abstract excerpt

Ferroptosis is a lytic form of regulated cell death that is driven by iron-dependent lipid peroxidation, and has been implicated in various diseases including acute kidney injury (AKI). Scutellarin is a flavonoid isolated from Erigeron breviscapus (Vant.) Hand.-Mazz. and possesses various pharmacological activities including anti-inflammatory and antioxidative properties. Yet it is unclear whether scutellarin can...

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Literature Corpus work: 764e4c5c-95a6-50e5-9637-2b67a656c766
DOI: 10.1101/2025.06.20.660655

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