Article

Targeted control of pneumolysin production by a mobile genetic element in <i>Streptococcus pneumoniae</i>

2020-06-16

Abstract excerpt

Streptococcus pneumoniae is a major human pathogen that can cause severe invasive diseases such as pneumonia, septicaemia and meningitis. Young children are at a particularly high risk, with an estimated half a million deaths worldwide in those under five attributable to invasive pneumococcal disease each year. The cytolytic toxin pneumolysin (Ply) is a primary virulence factor for this bacterium, yet despite its...

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Literature Corpus work: 76404689-b9e4-5f63-a02d-5777ddd1ce83
DOI: 10.1101/2020.06.16.154153

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