Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Transcriptional Regulator CpsY Is Important for Innate Immune Evasion in Streptococcus pyogenes.

Infection and immunity - 1 Mar 2017

Vega Luis A, Valdes Kayla M, Sundar Ganesh S, Belew Ashton T, Islam Emrul, Berge Jacob, Curry Patrick, Chen Steven, El-Sayed Najib M, Le Breton Yoann, McIver Kevin S

Abstract excerpt

As an exclusively human pathogen, Streptococcus pyogenes (the group A streptococcus [GAS]) has specifically adapted to evade host innate immunity and survive in multiple tissue niches, including blood. GAS can overcome the metabolic constraints of the blood environment and expresses various immunomodulatory factors necessary for survival and immune cell resistance. Here we present our investigation of one such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Host-Pathogen Interactions
Share to Immunity, Innate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophages

Share to Microbial Viability

Share to Neutrophils

Share to Streptococcal Infections

Share to Streptococcus pyogenes

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 27993974
DOI: 10.1128/IAI.00925-16
PMCID: PMC5328483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Transcriptional Regulator CpsY Is Important for Innate Immune Evasion in Streptococcus pyogenes.PMID 27993974Read ↗

Streptococcus pyogenes (“Group A Streptococcus”), a Highly Adapted Human Pathogen—Potential Implications of Its Virulence Regulation for Epidemiology and Disease ManagementSemantic proximity Read ↗

CpsY influences Streptococcus iniae cell wall adaptations important for neutrophil intracellular survival.Semantic proximity Read ↗

Insights into <i>Streptococcus Pyogenes</i> Pathogenesis from Transcriptome StudiesSemantic proximity Read ↗

Genome-wide protective response used by group A <i>Streptococcus</i> to evade destruction by human polymorphonuclear leukocytesSemantic proximity Read ↗

In silico characterisation of the two-component system regulators of Streptococcus pyogenes.Semantic proximity Read ↗

MsmR, a specific positive regulator of the Streptococcus pyogenes FCT pathogenicity region and cytolysin-mediated translocation system genes.Semantic proximity Read ↗

Transcription of the Streptococcus pyogenes hyaluronic acid capsule biosynthesis operon is regulated by previously unknown upstream elements.Semantic proximity Read ↗

Genome-wide identification of genes required for fitness of group A Streptococcus in human blood.Semantic proximity Read ↗

DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenesSemantic proximity Read ↗

Virulence factor regulation and regulatory networks in Streptococcus pyogenes and their impact on pathogen–host interactionsSemantic proximity Read ↗

Global transcriptional responses of pneumococcus to human blood components and cerebrospinal fluidSemantic proximity Read ↗

Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.