Article

<i>Pkd1</i> and <i>Wnt5a</i> genetically interact to control lymphatic vascular morphogenesis in mice

2021-04-01

Abstract excerpt

Lymphatic vascular development is regulated by well-characterised signalling and transcriptional pathways. These pathways regulate lymphatic endothelial cell (LEC) migration, motility, polarity and and morphogenesis. Canonical and non-canonical WNT signalling pathways are known to control LEC polarity and development of lymphatic vessels and valves. PKD1 , encoding Polycystin-1, is the most commonly mutated gene...

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Literature Corpus work: 76356264-37cf-5359-82e3-4964897e316b
DOI: 10.1101/2021.03.31.437795

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