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Article

Pkd1 regulates lymphatic vascular morphogenesis during development.

Cell reports - 8 May 2014

Coxam Baptiste, Sabine Amélie, Bower Neil I, Smith Kelly A, Pichol-Thievend Cathy, Skoczylas Renae, Astin Jonathan W, Frampton Emmanuelle, Jaquet Muriel, Crosier Philip S, Parton Robert G, Harvey Natasha L, Petrova Tatiana V, Schulte-Merker Stefan, Francois Mathias, Hogan Benjamin M

Abstract excerpt

Lymphatic vessels arise during development through sprouting of precursor cells from veins, which is regulated by known signaling and transcriptional mechanisms. The ongoing elaboration of vessels to form a network is less well understood. This involves cell polarization, coordinated migration, adhesion, mixing, regression, and shape rearrangements. We identified a zebrafish mutant, lymphatic and cardiac defects...

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Share to Embryonic Development
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Junctions

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Share to Polycystic Kidney, Autosomal Dominant

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Source

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Identifiers

PMID: 24767999
DOI: 10.1016/j.celrep.2014.03.063
PMCID: PMC5005109

Genes

PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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