Article

Comprehensive Mapping of Human dsRNAome Reveals Conservation, Neuronal Enrichment, and Intermolecular Interactions

2025-01-27

Abstract excerpt

<h4>SUMMARY</h4> The human transcriptome contains millions of A-to-I editing sites arising from an unclear number of poorly characterized dsRNAs. Editing sites are often used to infer presence of dsRNA, but this method is limited by transcription levels, read depth, ADAR expression and cannot identify unedited dsRNA. To address these limitations, we developed dsRNAscan. Applying dsRNAscan to the human genome pred...

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Literature Corpus work: 762979b5-0a49-5619-a631-d2a2d97e6a42
DOI: 10.1101/2025.01.24.634786

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