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Article

Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible.

BMC genomics - 10 Jul 2017

McKerrow Wilson H, Savva Yiannis A, Rezaei Ali, Reenan Robert A, Lawrence Charles E

Abstract excerpt

BACKGROUND: Repetitive elements are now known to have relevant cellular functions, including self-complementary sequences that form double stranded (ds) RNA. There are numerous pathways that determine the fate of endogenous dsRNA, and misregulation of endogenous dsRNA is a driver of autoimmune disease, particularly in the brain. Unfortunately, the alignment of high-throughput, short-read sequences to repeat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 28693467
DOI: 10.1186/s12864-017-3898-9
PMCID: PMC5502491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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