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Article

Genetic Underpinnings of Oligoasthenoteratozoospermia.

Clinical genetics - 1 Mar 2025

Feng Yanting, Liu Wensheng, Dong Junbo, Lu Fei, Wu Chunyan, Shao Qingting, Duan Aizhu, Yang Xinjie, Sun Ruipeng, Sha Yanwei, Wu Shihao, Wei Xiaoli

Abstract excerpt

Oligoasthenoteratozoospermia (OAT) is a frequent but severe type of male infertility. As one of the most multifaceted male infertility resulting from sperm problems, its genetic etiology remains unknown in most cases. In this review, we systematically sort out the latest literature on clinical reports and animal models leading to OAT, summarise the expression profiles of causative genes for OAT, and highlight the...

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Asthenozoospermia
OAT gene
Genetic Predisposition to Disease
Infertility, Male
Oligospermia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sperm and Testicular Function

Spermatogenesis

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Identifiers

PMID: 39780539
DOI: 10.1111/cge.14652

Genes

OAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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