Article
The NDUFS1/BRK1 Axis in COPD Pathogenesis: A Multi-Omics Approach Linking Mitochondrial Dysfunction to Actin Cytoskeleton Disruption
2026-03-18
Abstract excerpt
<title>Abstract</title> <p>Background: Chronic obstructive pulmonary disease (COPD) is a major global health burden, affecting over 300 million people and ranking as the third leading cause of death worldwide. Current therapies do not modify disease progression, and molecular mechanisms linking mitochondrial dysfunction and cytoskeletal disruption remain unclear. Emerging evidence implicates NDUFS1, a subunit of...
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Identifiers and source
- Literature Corpus work
- 75f2d6e1-264b-5d36-808d-757fcc678daa
- DOI
- 10.21203/rs.3.rs-8990913/v1
