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CYP1B1-Mediated Ferroptosis Defines a Biomarker and Therapeutic Target in COPD Across Multi-omics and Single-Cell

2026-01-01

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Chronic obstructive pulmonary disease (COPD) causes progressive airflow limitation and remains without disease-modifying therapy. Ferroptosis—iron-dependent lipid peroxidation—has emerged as a potential mechanism driving epithelial dysfunction and chronic inflammation; however, its upstream regulators in COPD remain incompletely defined. We hypothesized that...

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Literature Corpus work
58dded87-5053-5c0c-86b6-bee047355372
DOI
10.21203/rs.3.rs-8049999/v1
Open publication

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CYP1B1-Mediated Ferroptosis Defines a Biomarker and Therapeutic Target in COPD Across Multi-omics and Single-CellDOI 10.21203/rs.3.rs-8049999/v1
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