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Identification of biomarkers associated with mitochondrial dysfunction and programmed cell death in chronic obstructive pulmonary disease via transcriptomics

19 Jun 2025

Abstract excerpt

Background: Research has demonstrated that the homeostasis of mitochondria and programmed cell death (PCD) are intimately linked to chronic obstructive pulmonary disease (COPD). Consequently, identifying biomarkers of COPD from mitochondria-related genes (MRGs) and programmed cell death-related genes (PCD-RGs) is of paramount importance. Methods: Differentially expressed genes (DEGs) from the GSE42057 dataset and...

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PMID: 40612794
DOI: 10.3389/fgene.2025.1567173

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