Article
Added Value of Whole-Exome and Transcriptome Sequencing for Clinical Molecular Screenings of Advanced Cancer Patients With Solid Tumors.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Koeppel Florence, Bobard Alexandre, Lefebvre Céline, Pedrero Marion, Deloger Marc, Boursin Yannick, Richon Catherine, Chen-Min-Tao Romy, Robert Guillaume, Meurice Guillaume, Rouleau Etienne, Michiels Stefan, Massard Christophe, Scoazec Jean-Yves, Solary Eric, Soria Jean-Charles, André Fabrice, Lacroix Ludovic
Abstract excerpt
Comprehensive genomic profiling using high-throughput sequencing brings a wealth of information, and its place in the clinical setting has been increasingly prominent. This review emphasizes the utility of whole-exome sequencing (WES) and transcriptome sequencing (RNAseq) in patient care and clinical research, based on published reports as well as our experience with the MOSCATO-01 (MOlecular Screening for CAncer...
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