Article
Clinical application of whole-genome sequencing of solid tumors for precision oncology.
Experimental & molecular medicine - 1 Aug 2024
Kim Ryul, Kim Seokhwi, Oh Brian Baek-Lok, Yu Woo Sik, Kim Chang Woo, Hur Hoon, Son Sang-Yong, Yang Min Jae, Cho Dae Sung, Ha Taeyang, Heo Subin, Jang Jeon Yeob, Yun Jae Sung, Kwack Kyu-Sung, Kim Jai Keun, Huh Jimi, Lim Sun Gyo, Han Sang-Uk, Lee Hyun Woo, Park Ji Eun, Kim Chul-Ho, Roh Jin, Koh Young Wha, Lee Dakeun, Kim Jang-Hee, Lee Gil Ho, Noh Choong-Kyun, Jung Yun Jung, Park Ji Won, Sheen Seungsoo, Ahn Mi Sun, Choi Yong Won, Kim Tae-Hwan, Kang Seok Yun, Choi Jin-Hyuk, Baek Soo Yeon, Lee Kee Myung, Il Kim Sun, Noh Sung Hyun, Kim Se-Hyuk, Hwang Hyemin, Joo Eunjung, Lee Shinjung, Shin Jong-Yeon, Yun Ji-Young, Park Junggil, Yi Kijong, Kwon Youngoh, Lee Won-Chul, Park Hansol, Lim Joonoh, Yi Boram, Koo Jaemo, Koh June-Young, Lee Sangmoon, Lee Yuna, Lee Bo-Rahm, Connolly-Strong Erin, Ju Young Seok, Kwon Minsuk
Abstract excerpt
Genomic alterations in tumors play a pivotal role in determining their clinical trajectory and responsiveness to treatment. Targeted panel sequencing (TPS) has served as a key clinical tool over the past decade, but advancements in sequencing costs and bioinformatics have now made whole-genome sequencing (WGS) a feasible single-assay approach for almost all cancer genomes in clinical settings. This paper reports...
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